![]() ![]() If affected cats have adequate factor IX activity (eg 25-30%), they may have no symptoms until surgery or injury where prolonged bleeding occurs, though this can still be life-threatening. Severely affected cats (<5% activity of factor IX) bleed spontaneously and will usually die due to severe bleeding or anaemia. Regular episodes of bleeding may cause regenerative anaemia, due to loss of blood, and this may cause weakness, lethargy, irregular heartbeats and shortness of breath.Ĭats with haemophilia B can be severely affected if the activity of factor IX is very low extremely affected cats (<1% activity of factor IX) usually die at birth or shortly thereafter. Bleeding inside the eyes and into the brain can occur, and this can lead to blindness or neurological signs (signs of abnormal brain function). Internal bleeding may occur in organs or body cavities, resulting in bloody or dark vomit or stools, rectal or vaginal bleeding, nose bleeds, breathing difficulties, abnormal heart rhythm, swollen or distended abdomen and/or excessive thirst. Affected cats may show small spots of bleeding under the skin (only readily apparent in areas that are hairless and unpigmented) or inside the tissues of the mouth. The clinical signs of haemophilia B include episodes of lameness, swelling and bruising under the skin that resolve with no treatment, weakness, lack of appetite, fever and depression. Under these circumstances, affected animals show abnormally prolonged bleeding, because clot formation is ineffective. Typically, the problem shows after wounds caused by injury, trauma or surgery or through gum disease which causes bleeding. Haemophilia B is caused by a hereditary deficiency of the blood clotting protein, factor IX, one of the substances responsible for blood clotting. This process is critically important to seal open wounds, allowing them to stop bleeding and heal. Coagulation is the process of clot formation, when blood transforms from a free flowing liquid into a thickened gel like state, or clot. Haemophilia B is a rare blood disorder in which the blood is unable to clot properly, leading to excessive bleeding. ![]() ![]() (for more information click on the links below) Anaemia may also occur due to the loss of blood, contributing to weakness, lethargy, irregular heartbeats and shortness of breath. The clinical signs of haemophilia B include episodes of lameness, swelling and bruising under the skin, weakness, lack of appetite, fever and depression. Internal bleeding may occur in the organs. Prolonged bleeding can be initiated from injury, trauma and surgery. Haemophilia B is reported to be inherited in British shorthair cats, although it is uncommon.Ĭlinical signs usually appear in affected cats before 6 months of age. It is caused by a hereditary deficiency of the blood clotting protein, factor IX, one of the substances responsible for blood clotting. Outline: Haemophilia B is a rare blood disorder in which the blood is unable to clot properly, leading to excessive bleeding. VeNom term: Haemophilia (VeNom code: 924). ![]() Related terms: Factor IX deficiency Haemophilia B, coagulation disorder Christmas disease ![]()
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